Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | GALR1 | P47211 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770694 | 0.90 | GALR2 (0.40) | GALR2GALR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL23770453 | 0.89 | CYP1A2 (0.40) | GALR2GALR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL23770836 | 0.85 | MPL (0.33) | — | |
| SCHEMBL23770471 | 0.84 | SOS1 (0.34) | — | |
| SCHEMBL23770867 | 0.84 | PTPN11 (0.31) | GALR2GALR1 | |
| SCHEMBL23770765 | 0.82 | S1PR1 (0.35) | GALR2GALR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29464417 | 0.81 | SCN9A (0.36) | GALR2GALR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL19925203 | 0.81 | SCN9A (0.36) | GALR2GALR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL23770859 | 0.80 | CYP1A2 (0.44) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23770739 | 0.80 | CNR2 (0.38) | GALR2GALR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |