Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | GALR2 | O43603 | 1/20 | 0.30 |
| ▸ | GALR1 | P47211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770694 | 0.86 | GALR2 (0.40) | GALR2GALR1 | |
| SCHEMBL23770498 | 0.86 | CHRNA7 (0.31) | — | |
| SCHEMBL23770453 | 0.85 | CYP1A2 (0.40) | GALR2GALR1 | |
| SCHEMBL23770593 | 0.84 | GALR2 (0.33) | GALR2GALR1 | |
| SCHEMBL23770471 | 0.84 | SOS1 (0.34) | — | |
| SCHEMBL23770459 | 0.82 | BTK (0.34) | — | |
| SCHEMBL23770836 | 0.81 | MPL (0.33) | — | |
| SCHEMBL23770880 | 0.79 | RORC (0.41) | PTPN11 | |
| SCHEMBL23770739 | 0.77 | CNR2 (0.38) | PTPN11GALR2GALR1 | |
| SCHEMBL23770433 | 0.77 | PDE10A (0.36) | GALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |