Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970084 | 0.84 | BTK (0.33) | EIF2AK4BTKEPHX2 | |
| SCHEMBL19970085 | 0.84 | BTK (0.33) | EIF2AK4BTKEPHX2 | |
| SCHEMBL29464305 | 0.84 | SCN9A (0.32) | EIF2AK4BTKEPHX2 | |
| SCHEMBL29464459 | 0.84 | SCN9A (0.32) | EIF2AK4BTKEPHX2 | |
| SCHEMBL19951413 | 0.84 | SCN9A (0.32) | EIF2AK4BTKEPHX2 | |
| SCHEMBL29464531 | 0.84 | SCN9A (0.32) | EIF2AK4BTKEPHX2 | |
| SCHEMBL19951451 | 0.84 | SCN9A (0.32) | EIF2AK4BTKEPHX2 | |
| SCHEMBL19927721 | 0.84 | SCN9A (0.32) | EIF2AK4BTKEPHX2 | |
| SCHEMBL23770891 | 0.80 | BTK (0.33) | EIF2AK4BTKEPHX2 | |
| SCHEMBL23770748 | 0.80 | RORC (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |