Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 11/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22338125 | 0.74 | ADORA3 (0.34) | — | |
| SCHEMBL22338280 | 0.74 | TRPA1 (0.36) | — | |
| SCHEMBL22163370 | 0.74 | — | — | |
| SCHEMBL22338246 | 0.71 | RPS6KA3 (0.34) | TRPV1 | |
| SCHEMBL29464949 | 0.71 | XPO1 (0.44) | XPO1 | |
| SCHEMBL19968808 | 0.71 | XPO1 (0.44) | XPO1 | |
| SCHEMBL8989468 | 0.70 | XPO1 (0.58) | XPO1ADRB2TRPV1 | |
| SCHEMBL22163547 | 0.70 | NPC1 (0.32) | — | |
| SCHEMBL22338037 | 0.70 | — | — | |
| SCHEMBL11010121 | 0.70 | XPO1 (0.45) | XPO1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |