Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 2/20 | 0.40 |
| ▸ | SELP | P16109 | 2/20 | 0.40 |
| ▸ | SELE | P16581 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12233202 | 1.00 | FASN (0.42) | FASNMTNR1AMTNR1BCYP1A2ALOX15 | |
| SCHEMBL14752911 | 1.00 | FASN (0.42) | FASNMTNR1AMTNR1BCYP1A2ALOX15 | |
| SCHEMBL1663257 | 0.88 | FASN (0.50) | FASNMTNR1AMTNR1BCYP1A2ALOX15 | |
| SCHEMBL16001857 | 0.86 | MTNR1A (0.46) | FASNMTNR1AMTNR1BCYP1A2ALOX15 | |
| SCHEMBL18214990 | 0.85 | SELL (0.54) | FASNMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL16892330 | 0.85 | SELL (0.54) | FASNMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL16892296 | 0.85 | SELL (0.54) | FASNMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL23917734 | 0.83 | L3MBTL1 (0.50) | MTNR1AMTNR1BMEN1KMT2ASELL | |
| SCHEMBL14752929 | 0.80 | MTNR1A (0.42) | FASNMTNR1AMTNR1BCYP1A2ALOX15 | |
| SCHEMBL21501963 | 0.80 | MTNR1A (0.42) | FASNMTNR1AMTNR1BCYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160602-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-08-19 | — | — | WO | disclosed |