Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23775649 | 0.86 | CTSK (0.41) | CTSKLMNAL3MBTL1ANPEPCAPN1 | |
| SCHEMBL23775476 | 0.84 | ANPEP (0.41) | CTSKL3MBTL1ANPEPCAPN1ALDH1A1 | |
| SCHEMBL23775189 | 0.83 | CTSK (0.46) | NAMPTCTSKL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL23775478 | 0.82 | CAPN1 (0.45) | CTSKANPEPCAPN1KMT2A | |
| SCHEMBL23775642 | 0.81 | NAMPT (0.36) | NAMPTMAPK1CTSKANPEPCAPN1 | |
| SCHEMBL23775479 | 0.80 | ANPEP (0.39) | CTSKL3MBTL1ANPEPCAPN1ALDH1A1 | |
| SCHEMBL23775481 | 0.80 | ANPEP (0.44) | CTSKL3MBTL1ANPEPCAPN1ALDH1A1 | |
| SCHEMBL23775439 | 0.79 | CAPN1 (0.41) | CTSKL3MBTL1ANPEPCAPN1ALDH1A1 | |
| SCHEMBL23775483 | 0.79 | PSMB1 (0.40) | CTSKL3MBTL1ANPEPCAPN1ALDH1A1 | |
| SCHEMBL23755092 | 0.78 | ANPEP (0.42) | SCN9ATNKSPARP1TNKS2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021163631-A1 | CALPAIN-2 INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2021-08-19 | — | — | WO | disclosed |