Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 8/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23779078 | 0.91 | HRH4 (0.36) | HRH4GRM5POLBKCNH2KIT | |
| SCHEMBL23779140 | 0.90 | GRM5 (0.33) | HRH4GRM5POLB | |
| SCHEMBL23779087 | 0.85 | HRH4 (0.41) | HRH4GRM5KCNH2 | |
| SCHEMBL23779129 | 0.81 | HRH4 (0.51) | HRH4GRM5 | |
| SCHEMBL23779103 | 0.81 | HDAC6 (0.50) | HRH4POLB | |
| SCHEMBL23779084 | 0.80 | MAPK10 (0.39) | HRH4MMP9POLB | |
| SCHEMBL23779137 | 0.80 | HRH4 (0.39) | HRH4 | |
| SCHEMBL23779100 | 0.80 | HRH4 (0.42) | HRH4GRM5KCNH2 | |
| SCHEMBL23779073 | 0.79 | MMP9 (0.34) | HRH4MMP9GRM5KCNH2 | |
| SCHEMBL23779079 | 0.77 | HDAC6 (0.48) | HRH4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873910-A1 | 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV) | AiCuris GmbH & Co. KG (DE) | 2021-09-08 | — | — | EP | disclosed |