SCHEMBL2377939

SCHEMBL2377939

CC(C)CC(N)CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CACNA2D1 P54289 2/20 0.56
CACNB3 P54284 1/20 0.56
CACNA1C Q13936 1/20 0.56
PGR P06401 1/20 0.56
ADRA1A P35348 1/20 0.56
HTR2B P41595 1/20 0.56
CACNA2D2 Q9NY47 1/20 0.56
SLC7A5 Q01650 1/20 0.52
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
ANPEP P15144 4/20 0.44
ERAP1 Q9NZ08 2/20 0.44
ERAP2 Q6P179 1/20 0.44
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
THPO P40225 1/20 0.42
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2763515 1.00 CACNA2D1 (0.56) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL288273 1.00 CACNA2D1 (0.56) CACNA2D1CACNB3CACNA1CPGRADRA1A
Hydrochloric Acid SCHEMBL10977884 0.98 CACNA2D1 (0.54) CACNA2D1CACNB3CACNA1CPGRADRA1A
Hydrochloric Acid SCHEMBL10977886 0.98 CACNA2D1 (0.54) CACNA2D1CACNB3CACNA1CPGRADRA1A
Acetic Acid SCHEMBL2853697 0.95 CACNA2D1 (0.52) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL397004 0.85 GABRP (0.46) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL60920 0.85 GABRP (0.46) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL6061178 0.83 BHMT (0.44) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL8510926 0.83 CACNA2D1 (0.43) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL27553847 0.82 CACNA2D1 (0.41) CACNA2D1CACNB3CACNA1CPGRADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117147721-A Method for distinguishing fermented soybeans from fermented soybeans 中南林业科技大学 2023-12-01 CN claimed
US-20220077099-A1 COMPOSITION FOR CONDUCTIVE ADHESIVE, SEMICONDUCTOR PACKAGE COMPRISING CURED PRODUCT THEREOF, AND METHOD OF MANUFACTURING SEMICONDUCTOR PACKAGE USING THE SAME ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2022-03-10 US claimed
CN-104470925-B Imidazo-triazine formonitrile HCN as kinase inhibitor 百时美施贵宝公司 2017-12-05 CN claimed
CN-122070295-A Insect neuropeptide analogs 索拉斯塔生物有限公司 2026-05-19 CN disclosed
CN-122070296-A Insect neuropeptide analogs 索拉斯塔生物有限公司 2026-05-19 CN disclosed
EP-3455234-B1 SECO MACROLIDE COMPOUNDS SELVITA D O O (HR) 2026-04-01 EP disclosed
US-20250282908-A1 FLUX AGENT AND SEMICONDUCTOR PACKAGE INCLUDING CURED PRODUCT THEREOF ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2025-09-11 US disclosed
EP-4608842-A2 INSECT NEUROPEPTIDE ANALOGUES Solasta Bio Limited (GB) 2025-09-03 EP disclosed
US-12365706-B2 Macrocyclic peptides as potent inhibitors of K-RAS G12D mutant MERCK SHARP & DOHME LLC (US) 2025-07-22 US disclosed
CN-120202243-A Thermosetting resin composition, cured film, substrate, and electronic component 捷恩智株式会社 2025-06-24 CN disclosed
US-20250154325-A1 VANILLIC ACID-BASED ORGANIC-INORGANIC COMPOUND, CURABLE COMPOSITION, AND PRODUCTION METHOD THEREOF ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2025-05-15 US disclosed
US-5223516-A Endopeptidase inhibitors E. R. SQUIBB & SONS, INC. (US) 1993-06-29 US disclosed
US-5159081-A INTERMEDIATES OF PERIPHERALLY SELECTIVE N-CARBONYL-3,4,4-TRISUBSTITUTED PIPERIDINE OPIOID ANTAGONISTS ELI LILLY AND COMPANY (US) 1992-10-27 US disclosed
EP-0505467-A1 PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES Astra Pharmaceuticals Limited (GB) 1992-09-30 EP disclosed
EP-0506468-A1 N-substituted 4-phenyl-piperidine opioid-antagonists ELI LILLY AND COMPANY (US) 1992-09-30 EP disclosed
CN-1055735-A Trifluoromethyl mercaptan and mercapto acyl derivative and their using method SQUIBB & SONS INC (US) 1991-10-30 CN disclosed
EP-0449523-A1 Mercapto- or acylthio-trifluoromethyl amide derivatives and their use E.R. SQUIBB & SONS, INC. (US) 1991-10-02 EP disclosed
WO-1991008737-A2 PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES FISONS PLC (GB) 1991-06-27 WO disclosed
US-4242783-A Calender roll for use in super calender for magnetic tapes FUJI PHOTO FILM CO., LTD. (JP) 1981-01-06 US disclosed
US-4128673-A Method for super calendering magnetic recording elements FUJI PHOTO FILM CO., LTD. (JP) 1978-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12365706-B2 Macrocyclic peptides as potent inhibitors of K-RAS G12D mutant KRAS, NRAS, HRAS CACNA2D1 3433/4885CACNB3 4111/4885CACNA1C 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.