SCHEMBL23779797

SCHEMBL23779797

CC/C=C\C/C=C/c1cccc(OCCCCC)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.56
TLR2 O60603 2/20 0.56
TSHR P16473 1/20 0.50
CYSLTR2 Q9NS75 1/20 0.45
SMPD1 P17405 3/20 0.43
LTA4H P09960 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
AHR P35869 1/20 0.41
PLA2G4B P0C869 2/20 0.41
GPBAR1 Q8TDU6 1/20 0.41
GGPS1 O95749 1/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22122567 0.96 TLR4 (0.60) TLR4TLR2TSHRCYSLTR2LTA4H
SCHEMBL29440732 0.96 TLR4 (0.60) TLR4TLR2TSHRCYSLTR2LTA4H
SCHEMBL31538247 0.96 TLR4 (0.60) TLR4TLR2TSHRCYSLTR2LTA4H
SCHEMBL23779767 0.84 TLR4 (0.58) TLR4TLR2TSHRCYSLTR2LTA4H
SCHEMBL31336283 0.84 TLR4 (0.58) TLR4TLR2TSHRCYSLTR2LTA4H
SCHEMBL73717 0.83 TLR4 (0.55) TLR4TLR2TSHRKDM4EALDH1A1
SCHEMBL7541558 0.82 TLR4 (0.61) TLR4TLR2TSHRCYSLTR2SMPD1
SCHEMBL7539459 0.81 TLR4 (0.59) TLR4TLR2TSHRCYSLTR2SMPD1
SCHEMBL23779779 0.80 TLR4 (0.59) TLR4TLR2TSHRCYSLTR2LTA4H
SCHEMBL23779777 0.80 TLR4 (0.59) TLR4TLR2TSHRCYSLTR2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220002634-A1 ALKOXYBENZALDEHYDE DERIVATIVES AND PRECURSORS THEREOF GIVAUDAN SA (CH) 2022-01-06 US claimed
EP-3873880-A1 ALKOXYBENZALDEHYDE DERIVATIVES AND PRECURSORS THEREOF Givaudan SA (CH) 2021-09-08 EP claimed
CN-112930335-A Alkoxybenzaldehyde derivative and precursor thereof 奇华顿股份有限公司 2021-06-08 CN claimed
US-12018228-B2 Alkoxybenzaldehyde derivatives and precursors thereof GIVAUDAN SA (CH) 2024-06-25 US disclosed
EP-3873880-A1 ALKOXYBENZALDEHYDE DERIVATIVES AND PRECURSORS THEREOF Givaudan SA (CH) 2021-09-08 EP disclosed
CN-112930335-A Alkoxybenzaldehyde derivative and precursor thereof 奇华顿股份有限公司 2021-06-08 CN disclosed