SCHEMBL23780602

SCHEMBL23780602

CCOn1cccc1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MAPT P10636 3/20 0.34
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.34
ALOX12 P18054 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7158796 0.87 LMNA (0.35) L3MBTL1ALDH1A1MAPTLMNAMEN1
SCHEMBL6832383 0.86 LMNA (0.40) L3MBTL1POLBAPEX1TDP1HDAC4
SCHEMBL23780589 0.83 TSHR (0.41) L3MBTL1TDP1ALDH1A1MEN1KMT2A
SCHEMBL23798638 0.82 TSHR (0.43) TDP1ALDH1A1LMNAMEN1KMT2A
SCHEMBL5510858 0.81 POLB (0.39) L3MBTL1POLBAPEX1TDP1HDAC4
SCHEMBL28211649 0.81 ALDH1A1 (0.33) TDP1ALDH1A1MAPTLMNAMEN1
SCHEMBL23797983 0.80 TSHR (0.45) TDP1ALDH1A1LMNAMEN1KMT2A
SCHEMBL23798602 0.80 TSHR (0.45) TDP1ALDH1A1LMNAMEN1KMT2A
SCHEMBL23798651 0.80 TSHR (0.45) TDP1ALDH1A1LMNAMEN1KMT2A
SCHEMBL23798607 0.80 TSHR (0.45) TDP1ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed
CN-103282034-A Use of hematopoietic growth factor mimetics LIGAND PHARM INC 2013-09-04 CN disclosed
CN-102656141-A Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARM INC 2012-09-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI L3MBTL1 1279/4885POLB 2041/4885APEX1 3616/4885
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI L3MBTL1 1279/4885POLB 2041/4885APEX1 3616/4885
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI L3MBTL1 1279/4885POLB 2041/4885APEX1 3616/4885
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI L3MBTL1 1279/4885POLB 2041/4885APEX1 3616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.