SCHEMBL23780815

SCHEMBL23780815

O=C(O)C[C@H](Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.66
ADORA2A P29274 3/20 0.66
ADORA1 P30542 2/20 0.66
SLC6A2 P23975 1/20 0.66
SLC6A3 Q01959 1/20 0.66
ALDH1A1 P00352 2/20 0.64
PMP22 Q01453 2/20 0.64
NPC1 O15118 2/20 0.64
RAB9A P51151 2/20 0.64
RXFP1 Q9HBX9 2/20 0.64
TP53 P04637 1/20 0.64
CYP3A4 P08684 1/20 0.64
TSHR P16473 1/20 0.64
ALOX12 P18054 1/20 0.64
NFKB1 P19838 1/20 0.64
HIF1A Q16665 1/20 0.64
HPGD P15428 1/20 0.64
ADORA2B P29275 1/20 0.64
LMNA P02545 2/20 0.63
GLA P06280 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15698128 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL23780816 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL23787290 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL20099215 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL23780819 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL23787289 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL23780818 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL23780820 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL21631682 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3
SCHEMBL15700257 1.00 ADORA3 (0.66) ADORA3ADORA2AADORA1SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2249 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105647996-A Method for preparing adenosine triphosphate with immobilized enzyme method 深圳市古特新生生物科技有限公司 2016-06-08 CN claimed
CN-105567786-A Kit for detecting enzyme activity of thiopurine S-methyltransferase BEIJING ZHONGKE WEIXIN BIOMEDICAL RES INST CO LTD 2016-05-11 CN claimed
CN-105541754-A Preparation method of ATP (adenosine triphosphate) near infrared fluorescent probe UNIV NORTHWEST A&F 2016-05-04 CN claimed
CN-105504064-A PCNA(proliferating cell nuclear antigen) fusion protein and expression method and biotinylation method SUZHOU HAOOUBO BIOPHARMACEUTICAL CO LTD 2016-04-20 CN claimed
CN-105420157-A Preparation of escherichia coli competent cells and transformation method of escherichia coli competent cells SHENZHEN HONGKANG BIOLOGICAL TECH CO LTD 2016-03-23 CN claimed
CN-105296091-A Plant oil-based lubricant for precise casting parts WUXI YONGYI INVEST CASTING CO LTD 2016-02-03 CN claimed
CN-105255833-A Oral mucosa epithelium model and in-vitro construction method thereof SHAANXI BIOCELL BIOTECHNOLOGY CO LTD 2016-01-20 CN claimed
CN-103409757-B A kind of environment-friendly type brass work chemical brightening solution and preparation method thereof CNNC (TIANJIN) TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2016-01-20 CN claimed
CN-105263965-A Fusion proteins and methods for stimulating plant growth, protecting plants, and immobilizing bacillus spores on plants SPOGEN BIOTECH INC 2016-01-20 CN claimed
CN-105238745-A 3T3-L1 preadipocyte differentiation inducing reagent composition and application thereof UNIV SICHUAN AGRICULTURAL 2016-01-13 CN claimed
CN-1090677-C Capture assays SECR DEFENCE (GB) 2002-09-11 CN claimed
CN-1298948-A Process for synthesizing aminoformyl aspartic acid and its derivatives LANZHOU CHEM PHYS INST (CN) 2001-06-13 CN claimed
CN-1235135-A Gingko and chestnut fruit regulator GAO FENG (CN) 1999-11-17 CN claimed
CN-1231692-A Novel phytase and method for producing same KYOWA HAKKO KOGYO KK (JP) 1999-10-13 CN claimed
CN-1226602-A Fast culture media for mycobaterium tuberculosis and preparation thereof LIU ZHAOYUN (CN) 1999-08-25 CN claimed
CN-1216298-A Plant nutrient and its preparation QU JINGHUA (CN) 1999-05-12 CN claimed
CN-1164259-A Microbiological test method and reagent SECR DEFENCE BRIT (GB) 1997-11-05 CN claimed
CN-1157638-A Capture assays SECR DEFENCE (GB) 1997-08-20 CN claimed
CN-1139114-A Prepn process of adenosine triphosphate from hypoxanthine nucleotide LU CHUANZONG (CN) 1997-01-01 CN claimed
CN-1100468-A Rapid bacteria-checking liquid MOU ZIXIU (CN) 1995-03-22 CN claimed