Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698128 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL23780816 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL23787290 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL20099215 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL23780819 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL23787289 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL23780818 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL23780815 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL21631682 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 | |
| SCHEMBL15700257 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277005-A1 | PROANGIOGENIC COMPOSITIONS AND METHODS OF USE | UNIVERSITY OF NORTH DAKOTA | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277005-A1 | PROANGIOGENIC COMPOSITIONS AND METHODS OF USE | PGF, HDGF, VEGFA | ADORA3 836/4885ADORA2A 737/4885ADORA1 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.