Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327171 | 0.87 | HTT (0.47) | KDM4EHTTKMT2AMEN1NPC1 | |
| SCHEMBL11329067 | 0.86 | CES2 (0.48) | KDM4EHDAC6KMT2AMEN1NPC1 | |
| SCHEMBL6890595 | 0.83 | CES2 (0.41) | ATML3MBTL1HTTALDH1A1GAA | |
| SCHEMBL11318752 | 0.71 | CES2 (0.42) | ATML3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL11313782 | 0.70 | CES2 (0.41) | NPC1RAB9ANOS1CES2CES1 | |
| SCHEMBL11329102 | 0.70 | CES2 (0.41) | KMT2AMEN1RAB9ANOS1ALDH1A1 | |
| SCHEMBL1551882 | 0.68 | FURIN (0.46) | FURINATMTDP1L3MBTL1HDAC8 | |
| SCHEMBL7893716 | 0.67 | CES2 (0.48) | L3MBTL1KDM4EALDH1A1HSD17B10PARP1 | |
| SCHEMBL1077116 | 0.64 | PARP1 (0.50) | L3MBTL1KDM4EHTTKMT2AMEN1 | |
| SCHEMBL167439 | 0.64 | FURIN (0.43) | FURINATMTDP1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317238-A1 | Bis(Metallocene) Compounds and Catalyst Compositions Employing Such Compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-10-14 | — | — | US | disclosed |
| US-20210284767-A1 | Process for Preparing Polyethylene | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2021-09-16 | — | — | US | disclosed |
| US-20210277155-A1 | Process for Preparing Polypropylene | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2021-09-09 | — | — | US | disclosed |