SCHEMBL6890595

SCHEMBL6890595

CC(=C1C=CC=C1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.41
CES1 P23141 5/20 0.41
TSHR P16473 3/20 0.36
ALDH1A1 P00352 3/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
ESR1 P03372 1/20 0.35
CASP1 P29466 1/20 0.35
BRCA1 P38398 1/20 0.35
CASP7 P55210 1/20 0.35
HBB P68871 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 1/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ATM Q13315 1/20 0.33
HSP90AA1 P07900 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23780939 0.83 FURIN (0.38) CES2CES1ALDH1A1HSD17B10HTT
SCHEMBL11318752 0.78 CES2 (0.42) CES2CES1TSHRALDH1A1MAPT
SCHEMBL16411457 0.78 ALDH1A1 (0.42) CES2CES1ALDH1A1MAPTLMNA
SCHEMBL11329407 0.76 TPMT (0.39)
SCHEMBL11313782 0.76 CES2 (0.41) CES2CES1MAPTLMNA
SCHEMBL11327171 0.76 HTT (0.47) TSHRALDH1A1MAPTHTTGAA
SCHEMBL11329067 0.74 CES2 (0.48) CES2CES1ALDH1A1LMNA
SCHEMBL647841 0.74 TDP1 (0.40) CES2CES1TSHRALDH1A1DAO
SCHEMBL7893716 0.73 CES2 (0.48) CES2CES1TSHRALDH1A1ESR1
SCHEMBL27827291 0.72 MAPT (0.37) CES2CES1TSHRALDH1A1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058812-A Double-active-center metallocene complex and preparation method and application thereof 万华化学集团股份有限公司 2025-05-30 CN claimed
US-6326445-B1 REACTION PRODUCT CONTAINING FULVENE COMPOUND UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2001-12-04 US claimed
US-6054405-A CONTAINING A FLUVENE COMPOUND UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-04-25 US claimed
EP-0927728-A1 Catalyst composition for the polymerization of olefins UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-07-07 EP claimed
US-5554795-A Process for preparing cyclopentadienyl-type ligands PHILLIPS PETROLEUM COMPANY (US) 1996-09-10 US claimed
US-5349100-A Chiral metallocene compounds and preparation thereof by creation of a chiral center by enantioselective hydride transfer EXXON CHEMICAL PATENTS INC. (US) 1994-09-20 US claimed
WO-1992012112-A1 CHIRAL METALLOCENE COMPOUNDS AND PREPARATION THEREOF BY CREATION OF A CHIRAL CENTER BY ENANTIOSELECTIVE HYDRIDE TRANSFER EXXON CHEMICAL PATENTS INC. (US) 1992-07-23 WO claimed
US-4786689-A Process for metallating nonconjugated diene-containing ethylene polymers and graft polymers prepared therefrom THE DOW CHEMICAL COMPANY (US) 1988-11-22 US claimed
US-4246167-A FULVENES AND AN ACID CATALYST ASHLAND OIL, INC. (US) 1981-01-20 US claimed
JP-11322775-A None JP disclosed
EP-4375353-B1 VISCOSITY MODIFIER FOR LUBRICATING OIL, AND LUBRICATING OIL COMPOSITION FOR HYDRAULIC OIL MITSUI CHEMICALS INC (JP) 2026-05-27 EP disclosed
US-12398338-B2 Viscosity modifier for lubricating oil and lubricating oil composition for hydraulic fluid MITSUI CHEMICALS, INC. (JP) 2025-08-26 US disclosed
CN-120058812-A Double-active-center metallocene complex and preparation method and application thereof 万华化学集团股份有限公司 2025-05-30 CN disclosed
US-20250171704-A1 LUBRICATING OIL COMPOSITION MITSUI CHEMICALS, INC. (JP) 2025-05-29 US disclosed
US-4424123-A Ore flotation using fulvenes PHILLIPS PETROLEUM COMPANY (US) 1984-01-03 US disclosed
US-4412088-A CURABLE BINDER COMPOSITIONS ASHLAND OIL, INC. (US) 1983-10-25 US disclosed
US-4394466-A AGGREGATES, METAL CARBOXYLATE CATALYST ASHLAND OIL, INC. (US) 1983-07-19 US disclosed
US-4390675-A EPOXYFULVENE, ACID CATALYST ASHLAND OIL, INC. (US) 1983-06-28 US disclosed
US-4320218-A CURABLE FULRENES AND A METAL SALT CATALYST ASHLAND OIL, INC. (US) 1982-03-16 US disclosed
US-4246167-A FULVENES AND AN ACID CATALYST ASHLAND OIL, INC. (US) 1981-01-20 US disclosed