SCHEMBL23781981

SCHEMBL23781981

C=C[C@H](C)OCCOCCCC

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
CYP3A4 P08684 1/20 0.39
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 2/20 0.34
HSD17B10 Q99714 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7563361 0.94 HTT (0.44) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL822765 0.87
SCHEMBL14564083 0.87 ALDH1A1 (0.31) TSHRHSD17B10ALDH1A1
SCHEMBL1378620 0.81 DNM1 (0.42) TSHRHPGDALDH1A1
SCHEMBL23781883 0.81 ALDH1A1 (0.33) TSHRTHRBALDH1A1
SCHEMBL10535267 0.80
SCHEMBL5073007 0.79 DNM1 (0.45) TSHRMAPTMEN1THRBHTT
SCHEMBL14232137 0.79 DNM1 (0.45) TSHRMAPTMEN1THRBHTT
SCHEMBL10494286 0.79 DNM1 (0.45) TSHRMAPTMEN1THRBHTT
SCHEMBL27668890 0.79 DNM1 (0.45) TSHRMAPTMEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4069667-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATE Firmenich SA (CH) 2022-10-12 EP disclosed
WO-2021176009-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATE FIRMENICH SA (CH) 2021-09-10 WO disclosed