SCHEMBL23781985

SCHEMBL23781985

Cc1ccccc1N1CCN(c2ccccc2C)C1=[Ru](Cl)(Cl)=Cc1cc([N+](=O)[O-])ccc1OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.38
ALDH1A1 P00352 6/20 0.38
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 4/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
DRD2 P14416 1/20 0.38
ADRA1D P25100 1/20 0.38
ADRA1A P35348 1/20 0.38
ADRA1B P35368 1/20 0.38
CYP19A1 P11511 2/20 0.35
SLC6A5 Q9Y345 1/20 0.35
CCR5 P51681 1/20 0.34
PKM P14618 1/20 0.34
DUSP3 P51452 1/20 0.34
PTPN5 P54829 1/20 0.34
PTPN11 Q06124 1/20 0.34
HTT P42858 2/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1194744 0.86 CYP19A1 (0.35) MAPK1ALDH1A1TDP1LMNAMAPT
SCHEMBL29380873 0.86 CYP19A1 (0.35) MAPK1ALDH1A1TDP1LMNAMAPT
SCHEMBL29860905 0.83 MAPK1 (0.38) MAPK1ALDH1A1TDP1LMNAMAPT
SCHEMBL34469514 0.82 ADRA1D (0.34) DRD2ADRA1DADRA1AADRA1B
SCHEMBL2587303 0.82 ADRA1D (0.34) DRD2ADRA1DADRA1AADRA1B
SCHEMBL3443411 0.75 MAPT (0.32) MAPTDRD2ADRA1DADRA1AADRA1B
SCHEMBL23781890 0.75 CYP19A1 (0.35) ALDH1A1TDP1LMNAMAPTSMN1; SMN2
SCHEMBL29028906 0.74 CYP19A1 (0.36) ALDH1A1TDP1LMNAMAPTSMN1; SMN2
SCHEMBL29886561 0.72 CYP19A1 (0.35) MAPK1ALDH1A1TDP1MAPTHPGD
SCHEMBL14995111 0.72 P2RX7 (0.34) ADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021176009-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATE FIRMENICH SA (CH) 2021-09-10 WO disclosed