SCHEMBL23786254

SCHEMBL23786254

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nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 12/20 0.64
▸ NAALAD2 Q9Y3Q0 7/20 0.64
▸ RIMKLA Q8IXN7 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23786176 0.90 FOLH1 (0.72) FOLH1NAALAD2RIMKLA
SCHEMBL26830758 0.88 FOLH1 (0.64) FOLH1NAALAD2RIMKLA
SCHEMBL2552007 0.82 FOLH1 (0.62) FOLH1NAALAD2RIMKLA
SCHEMBL2552010 0.82 FOLH1 (0.62) FOLH1NAALAD2RIMKLA
SCHEMBL23786228 0.82 FOLH1 (0.55) FOLH1NAALAD2RIMKLA
SCHEMBL22054657 0.81 FOLH1 (0.72) FOLH1NAALAD2RIMKLA
SCHEMBL22054340 0.81 FOLH1 (0.72) FOLH1NAALAD2RIMKLA
SCHEMBL23786248 0.80 FOLH1 (0.57) FOLH1NAALAD2RIMKLA
SCHEMBL18161468 0.80 FOLH1 (1.00) FOLH1NAALAD2RIMKLA
SCHEMBL14102890 0.80 FOLH1 (1.00) FOLH1NAALAD2RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210276981-A1 COVALENT IMMUNE RECRUITER COMPOUNDS FOR IMMUNE CELL RECOGNITION AND ASSOCIATED USES MCMASTER UNIVERSITY (CA) 2021-09-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210276981-A1 COVALENT IMMUNE RECRUITER COMPOUNDS FOR IMMUNE CELL RECOGNITION AND ASSOCIATED USES CD74, CD4, HLA-A FOLH1 3787/4885NAALAD2 536/4885RIMKLA 770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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