SCHEMBL2552007

SCHEMBL2552007

CC(C)(C)C(=O)NC(CCC(=O)O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 8/20 0.62
▸ NAALAD2 Q9Y3Q0 5/20 0.62
▸ RIMKLA Q8IXN7 1/20 0.62
▸ GGH Q92820 1/20 0.49
▸ GAA P10253 1/20 0.44
▸ FNTA P49354 2/20 0.43
▸ FNTB P49356 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552010 1.00 FOLH1 (0.62) FOLH1NAALAD2RIMKLAGGHGAA
SCHEMBL29538498 0.85 FOLH1 (0.58) FOLH1NAALAD2RIMKLAGGHGAA
SCHEMBL18876678 0.84 NOD1 (0.46) FOLH1NAALAD2RIMKLA
SCHEMBL21911518 0.84 FOLH1 (0.56) FOLH1NAALAD2RIMKLAGGH
SCHEMBL8738364 0.82 FPR2 (0.44) FOLH1NAALAD2RIMKLA
SCHEMBL23786254 0.82 FOLH1 (0.64) FOLH1NAALAD2RIMKLA
SCHEMBL26830758 0.82 FOLH1 (0.64) FOLH1NAALAD2RIMKLA
SCHEMBL28428784 0.81 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGH
SCHEMBL28428786 0.81 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGH
SCHEMBL29538289 0.81 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3473249-A1 CROSSLINKABLE DENDRIMERS Wayne State University (US) 2019-04-24 — — EP claimed
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 — — US claimed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 — — US claimed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 — — US claimed
EP-2552458-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Wayne State University (US) 2013-02-06 — — EP claimed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 — — WO claimed
US-11446238-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2022-09-20 — — US disclosed
EP-3473249-A1 CROSSLINKABLE DENDRIMERS Wayne State University (US) 2019-04-24 — — EP disclosed
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 — — US disclosed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 — — US disclosed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 — — US disclosed
EP-2552458-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Wayne State University (US) 2013-02-06 — — EP disclosed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 — — WO disclosed
US-20110008396-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR CONDITIONS RUTGERS, THE SATE UNIVERSITY OF NEW JERSEY (US) 2011-01-13 — — US disclosed
US-20110008396-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR CONDITIONS RUTGERS, THE SATE UNIVERSITY OF NEW JERSEY (US) 2011-01-13 — — US disclosed
US-20080288176-A1 Development of Prodrugs Possessing a Nitric Oxide Donor Diazen-1-Ium-1,2-Diolate Noiety Using in Vitro/in Silico Predictions TAM YUN KAU 2008-11-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES PAM, UACA, FLT1 FOLH1 3470/4885NAALAD2 2213/4885RIMKLA 2047/4885
US-20110008396-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR CONDITIONS APOB, FABP3, LIPA FOLH1 982/4885NAALAD2 1320/4885RIMKLA 3695/4885
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES UACA, PAM, JAK3 FOLH1 2813/4885NAALAD2 2726/4885RIMKLA 2369/4885
US-11446238-B2 Injectable dendrimer hydrogel nanoparticles PAM, UACA, FLT1 FOLH1 3470/4885NAALAD2 2213/4885RIMKLA 2047/4885
US-20080288176-A1 Development of Prodrugs Possessing a Nitric Oxide Donor Diazen-1-Ium-1,2-Diolate Noiety Using in Vitro/in Silico Predictions NOS1, NOS2, NOS3 FOLH1 1777/4885NAALAD2 472/4885RIMKLA 880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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