SCHEMBL2552010

SCHEMBL2552010

CC(C)(C)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 8/20 0.62
▸ NAALAD2 Q9Y3Q0 5/20 0.62
▸ RIMKLA Q8IXN7 1/20 0.62
▸ GGH Q92820 1/20 0.49
▸ GAA P10253 1/20 0.44
▸ FNTA P49354 2/20 0.43
▸ FNTB P49356 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552007 1.00 FOLH1 (0.62) FOLH1NAALAD2RIMKLAGGHGAA
SCHEMBL29538498 0.85 FOLH1 (0.58) FOLH1NAALAD2RIMKLAGGHGAA
SCHEMBL18876678 0.84 NOD1 (0.46) FOLH1NAALAD2RIMKLA
SCHEMBL21911518 0.84 FOLH1 (0.56) FOLH1NAALAD2RIMKLAGGH
SCHEMBL8738364 0.82 FPR2 (0.44) FOLH1NAALAD2RIMKLA
SCHEMBL23786254 0.82 FOLH1 (0.64) FOLH1NAALAD2RIMKLA
SCHEMBL26830758 0.82 FOLH1 (0.64) FOLH1NAALAD2RIMKLA
SCHEMBL28428784 0.81 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGH
SCHEMBL28428786 0.81 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGH
SCHEMBL29538289 0.81 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3473249-A1 CROSSLINKABLE DENDRIMERS Wayne State University (US) 2019-04-24 — — EP claimed
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 — — US claimed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 — — US claimed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 — — US claimed
EP-2552458-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Wayne State University (US) 2013-02-06 — — EP claimed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 — — WO claimed
US-20250289842-A1 Processes for Making NAG-25, a Carbohydrate Targeting Moiety, and its Intermediates AMGEN INC. 2025-09-18 — — US disclosed
EP-4519278-A1 PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES Amgen Inc. (US) 2025-03-12 — — EP disclosed
CN-119562958-A Methods for preparing NAG-25 carbohydrate targeting moieties and intermediates thereof 安进公司 2025-03-04 — — CN disclosed
WO-2023215306-A1 PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES AMGEN INC. (US) 2023-11-09 — — WO disclosed
WO-2023215306-A1 PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES AMGEN INC. (US) 2023-11-09 — — WO disclosed
US-11446238-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2022-09-20 — — US disclosed
EP-3473249-A1 CROSSLINKABLE DENDRIMERS Wayne State University (US) 2019-04-24 — — EP disclosed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 — — WO disclosed
US-20070037821-A1 Nitrosated glutamic acid compounds, compositions and methods of use NITROMED, INC. (US) 2007-02-15 — — US disclosed
EP-1673384-A4 NITROSATED GLUTAMIC ACID COMPOUNDS, COMPOSITIONS AND METHODS OF USE NITROMED INC (US) 2007-02-07 — — EP disclosed
EP-1673384-A2 NITROSATED GLUTAMIC ACID COMPOUNDS, COMPOSITIONS AND METHODS OF USE Nitromed, Inc. (US) 2006-06-28 — — EP disclosed
WO-2005030135-A2 NITROSATED GLUTAMIC ACID COMPOUNDS, COMPOSITIONS AND METHODS OF USE NITROMED, INC. (US) 2005-04-07 — — WO disclosed
US-6867316-B2 Platinum(II) complexes of N-substituted amino dicarboxylates and the preparation method thereof BOARD OF TRUSTEES, EWHA WOMANS UNIVERSITY (KR) 2005-03-15 — — US disclosed
US-20040162342-A1 Platinum(II) complexes of N-substituted amino dicarboxylates and the preparation method thereof BOARD OF TRUSTEES, EWHA WOMANS UNIVERSITY (KR) 2004-08-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289842-A1 Processes for Making NAG-25, a Carbohydrate Targeting Moiety, and its Intermediates ENGASE, MAN2B2, GALNT2 FOLH1 85/4885NAALAD2 37/4885RIMKLA 703/4885
US-20040162342-A1 Platinum(II) complexes of N-substituted amino dicarboxylates and the preparation method thereof DAO, DDO, PRMT1 FOLH1 348/4885NAALAD2 671/4885RIMKLA 514/4885
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES PAM, UACA, FLT1 FOLH1 3470/4885NAALAD2 2213/4885RIMKLA 2047/4885
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES UACA, PAM, JAK3 FOLH1 2813/4885NAALAD2 2726/4885RIMKLA 2369/4885
US-11446238-B2 Injectable dendrimer hydrogel nanoparticles PAM, UACA, FLT1 FOLH1 3470/4885NAALAD2 2213/4885RIMKLA 2047/4885
US-20070037821-A1 Nitrosated glutamic acid compounds, compositions and methods of use GLS, NOS2, NOS1 FOLH1 112/4885NAALAD2 164/4885RIMKLA 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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