SCHEMBL23786258

SCHEMBL23786258

CCN(CC)c1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)nc(C(C)C)n1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CFTR P13569 7/20 0.43
TERT O14746 2/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
USP2 O75604 1/20 0.39
HTT P42858 1/20 0.39
AURKA O14965 1/20 0.39
AURKB Q96GD4 1/20 0.39
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
JAK1 P23458 1/20 0.37
JAK3 P52333 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23786206 0.86 MAPT (0.48) RAB9AALDH1A1MAPTUSP2HTT
SCHEMBL23666320 0.83 RAB9A (0.44) RAB9ACA1CA2CA9CFTR
SCHEMBL23786262 0.80 MAPT (0.46) ALDH1A1MAPTHTTAURKAAURKB
SCHEMBL23666321 0.80 MAPT (0.47) ALDH1A1MAPTAURKAAURKBJAK1
SCHEMBL12483971 0.76 HTT (0.41) ALDH1A1MAPTHTTAURKAAURKB
SCHEMBL23786208 0.74 SMN1; SMN2 (0.36) RAB9ACA1CA2CA9ALDH1A1
SCHEMBL24701216 0.72 MAPT (0.41) RAB9AALDH1A1MAPTHTTAURKA
SCHEMBL15501260 0.71 AURKA (0.51) RAB9AALDH1A1MAPTUSP2HTT
SCHEMBL1392662 0.70 POLB (0.51) CA1CA2CA9ALDH1A1MAPT
SCHEMBL23786325 0.70 CA1 (0.48) RAB9ACA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220332970-A1 PHOTOSENSITIVE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-10-20 US disclosed
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed