SCHEMBL23786262

SCHEMBL23786262

CC(C)c1nc(O)nc(Nc2ccc3[nH]c(=O)[nH]c3c2)n1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.46
ALDH1A1 P00352 5/20 0.46
AURKA O14965 1/20 0.44
AURKB Q96GD4 1/20 0.44
BCL6 P41182 6/20 0.42
BCOR Q6W2J9 6/20 0.42
KDM4E B2RXH2 2/20 0.42
GAA P10253 1/20 0.42
JAK1 P23458 1/20 0.40
JAK3 P52333 1/20 0.40
HTT P42858 1/20 0.40
MAPK1 P28482 1/20 0.40
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
HBB P68871 1/20 0.39
KMT2A Q03164 1/20 0.39
XDH P47989 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23786206 0.91 MAPT (0.48) MAPTALDH1A1AURKAAURKBBCL6
SCHEMBL21925305 0.87 AURKA (0.48) MAPTALDH1A1AURKAAURKBBCL6
SCHEMBL23666321 0.85 MAPT (0.47) MAPTALDH1A1AURKAAURKBBCL6
SCHEMBL23786258 0.80 RAB9A (0.43) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL23139623 0.80 KDM4E (0.42) MAPTALDH1A1AURKAAURKBBCL6
SCHEMBL24701216 0.78 MAPT (0.41) MAPTALDH1A1AURKAAURKBBCL6
SCHEMBL21635756 0.78 BCL6 (0.56) MAPTALDH1A1AURKAAURKBBCL6
SCHEMBL21927159 0.77 AURKA (0.47) MAPTALDH1A1AURKAAURKBBCL6
SCHEMBL21635754 0.77 BCL6 (0.52) MAPTALDH1A1AURKAAURKBBCL6
SCHEMBL21635743 0.76 DDX3X (0.50) MAPTALDH1A1AURKAAURKBBCL6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed