SCHEMBL23786265

SCHEMBL23786265

CCN(CC)CCCNC(=O)c1cc(NC(=O)c2c3ccccc3c(C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)c3ccccc23)cc(C(=O)NCCCN(CC)CC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
MAPT P10636 4/20 0.46
MAPK1 P28482 1/20 0.46
TSHR P16473 1/20 0.46
ALDH1A1 P00352 4/20 0.44
KLK7 P49862 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HSD17B10 Q99714 3/20 0.43
HPGD P15428 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
XDH P47989 1/20 0.43
TP53 P04637 1/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19012214 0.87 MAPT (0.47) KDM4EMAPTMAPK1TSHRALDH1A1
SCHEMBL24414555 0.82 IGF1R (0.48) KDM4EMAPTMAPK1TSHRRXFP1
SCHEMBL21342264 0.79 MAPT (0.42) KDM4EMAPTMAPK1TSHRALDH1A1
SCHEMBL20011618 0.79 MAPT (0.42) KDM4EMAPTMAPK1TSHRALDH1A1
SCHEMBL23156902 0.79 KDM4E (0.42) KDM4EMAPTMAPK1TSHRALDH1A1
SCHEMBL16359970 0.79 MAPT (0.42) KDM4EMAPTMAPK1TSHRALDH1A1
SCHEMBL15746557 0.79 KDM4E (0.42) KDM4EMAPTMAPK1TSHRALDH1A1
SCHEMBL216448 0.79 ALDH1A1 (0.52) KDM4EMAPTMAPK1ALDH1A1KLK7
SCHEMBL25047061 0.79 IGF1R (0.44) KDM4EMAPTMAPK1TSHRRXFP1
SCHEMBL14756621 0.78 TDP1 (0.43) KDM4EMAPTMAPK1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed