Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.52 |
| ▸ | CDK2 | P24941 | 4/20 | 0.52 |
| ▸ | PI4KA | P42356 | 4/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | HINT1 | P49773 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26795778 | 0.86 | PI4KA (0.42) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL23786519 | 0.82 | CDK1 (0.58) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL21118446 | 0.82 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL24835829 | 0.81 | CDK1 (0.54) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL12994241 | 0.79 | PI4KA (0.62) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL26622982 | 0.78 | KDM4E (0.36) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL21090694 | 0.76 | MEN1 (0.47) | — | |
| SCHEMBL22020877 | 0.75 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL22666442 | 0.74 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL27057976 | 0.74 | PI4KA (0.35) | CDK1CCNB1CCNE1CDK2PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277046-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277046-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | STING1, CGAS, IFNAR1 | CDK1 1709/4885CCNB1 1774/4885CCNE1 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.