SCHEMBL26622982

SCHEMBL26622982

CCCC(C)(CC)n1cnc2cnc(N)nc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
ADRA1A P35348 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
HDAC6 Q9UBN7 2/20 0.34
NUDT1 P36639 4/20 0.33
IRAK4 Q9NWZ3 4/20 0.33
PI4KA P42356 1/20 0.32
PI4K2B Q8TCG2 1/20 0.32
PI4K2A Q9BTU6 1/20 0.32
PI4KB Q9UBF8 1/20 0.32
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNE1 P24864 1/20 0.31
CDK2 P24941 1/20 0.31
PIK3R1 P27986 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26638943 0.91 KDM4E (0.34) KDM4EALDH1A1HPGDADRA1AHSD17B10
SCHEMBL26607533 0.90 KDM4E (0.34) KDM4EALDH1A1HPGDADRA1AHSD17B10
SCHEMBL26607564 0.82 KDM4E (0.39) KDM4EALDH1A1HPGDADRA1AHSD17B10
SCHEMBL14616264 0.79 PI4KA (0.45) KDM4EALDH1A1HPGDADRA1AHSD17B10
SCHEMBL23786398 0.78 CDK1 (0.52) HSP90AA1HSP90AB1PI4KAPI4K2BPI4K2A
SCHEMBL21118430 0.77 FDPS (0.39) ALDH1A1HSD17B10HDAC6IRAK4PI4KA
SCHEMBL21118446 0.70 PI4KA (0.67) ALDH1A1PI4KAPI4K2BPI4K2API4KB
SCHEMBL26795778 0.70 PI4KA (0.42) HSP90AA1HSP90AB1PI4KAPI4K2BPI4K2A
SCHEMBL14010824 0.70 KDM4E (0.55) KDM4EALDH1A1HPGDADRA1AHSD17B10
SCHEMBL14642669 0.69 CDK1 (0.56) KDM4EALDH1A1HPGDADRA1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof CAT, MPO, NISCH KDM4E 4759/4885ALDH1A1 2110/4885HPGD 795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.