Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.42 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 4/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23786398 | 0.86 | CDK1 (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL23476827 | 0.83 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBNT5E | |
| SCHEMBL13389895 | 0.80 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KBNT5E | |
| SCHEMBL21118446 | 0.80 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL24835829 | 0.78 | CDK1 (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| SCHEMBL21090694 | 0.74 | MEN1 (0.47) | LMNAHIF1A | |
| SCHEMBL22020877 | 0.73 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22666442 | 0.72 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| SCHEMBL27057976 | 0.72 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KBCDK1 | |
| SCHEMBL24980488 | 0.72 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374058-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374058-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | EHMT1, POLRMT, RNASE1 | PI4KA 829/4885PI4K2B 1230/4885PI4K2A 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.