Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546259 | 0.84 | CHAT (0.47) | CHATMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL3314625 | 0.84 | CHAT (0.47) | CHATMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL1682034 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1GAAKMT2ACLCN2 | |
| SCHEMBL21299263 | 0.77 | KDM4E (0.38) | MAPTALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL22058627 | 0.77 | TDP1 (0.52) | MAPTALDH1A1GAAKMT2APOLB | |
| SCHEMBL12503862 | 0.77 | KDM4E (0.38) | MAPTALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL318156 | 0.76 | CHAT (0.54) | CHATPTGER4PTGER3PTGER2 | |
| SCHEMBL318157 | 0.76 | CHAT (0.54) | CHATPTGER4PTGER3PTGER2 | |
| SCHEMBL5690553 | 0.76 | NFE2L2 (0.46) | SIGMAR1 | |
| SCHEMBL5690556 | 0.76 | NFE2L2 (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604384-B1 | HYDROPHILIC POLYMER DERIVATIVE HAVING SELF-IMMOLATIVE ACETAL LINKER AND COMPOSITE USING SAME | NOF CORP (JP) | 2021-09-08 | — | — | EP | disclosed |