Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SNCA | P37840 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.48 |
| ▸ | MPL | P40238 | 3/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787623 | 0.87 | ALDH1A1 (0.66) | THRBAPPMAPTSNCAHPGD | |
| SCHEMBL23787724 | 0.84 | CYP1A2 (0.54) | THRBAPPMAPTSNCACYP1A2 | |
| SCHEMBL23787690 | 0.82 | MPL (0.51) | THRBCYP1A2HPGDMEN1ALDH1A1 | |
| SCHEMBL23787678 | 0.82 | PHLPP2 (0.55) | THRBAPPMAPTSNCACYP1A2 | |
| SCHEMBL23787546 | 0.82 | ALDH1A1 (0.53) | THRBAPPMAPTSNCACYP1A2 | |
| SCHEMBL23787782 | 0.81 | CYP1A2 (0.54) | THRBAPPMAPTSNCACYP1A2 | |
| SCHEMBL23787780 | 0.81 | PHLPP2 (0.67) | THRBAPPMAPTSNCACYP1A2 | |
| SCHEMBL23787723 | 0.80 | APP (0.75) | THRBAPPMAPTSNCACYP1A2 | |
| SCHEMBL23787676 | 0.79 | CYP1A2 (0.52) | THRBAPPMAPTSNCACYP1A2 | |
| E122 SCHEMBL345295 | 0.79 | CYP1A2 (0.78) | THRBAPPMAPTSNCACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | ACIBADEM MEHMET ALI AYDINLAR UNIVERSITESI (TR) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | POLG, POLB, POLA1 | THRB 2774/4885APP 3911/4885MAPT 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.