E122

E122

SCHEMBL345295

O=S(=O)(O)c1ccc(N=Nc2cc(S(=O)(=O)O)c3ccccc3c2O)c2ccccc12

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.78
THRB P10828 3/20 0.72
CTRB1 P17538 1/20 0.72
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
MPL P40238 3/20 0.56
CTRC Q99895 1/20 0.56
HPGD P15428 2/20 0.53
BLM P54132 2/20 0.53
ALDH1A1 P00352 1/20 0.53
APP P05067 1/20 0.53
MAPT P10636 1/20 0.53
ALOX12 P18054 1/20 0.53
SNCA P37840 1/20 0.53
RECQL P46063 1/20 0.53
HIF1A Q16665 1/20 0.53
SUMO2 P61956 4/20 0.52
SUMO1 P63165 4/20 0.52
SENP7 Q9BQF6 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E122 SCHEMBL110093 1.00 CYP1A2 (0.78) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL185359 0.98 CYP1A2 (0.76) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL185360 0.98 CYP1A2 (0.76) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL4806652 0.98 CYP1A2 (0.76) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL4806638 0.90 THRB (0.90) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL3208444 0.90 THRB (0.90) CYP1A2THRBCTRB1MEN1KMT2A
SCHEMBL8947091 0.89 CYP1A2 (0.71) CYP1A2THRBCTRB1MEN1KMT2A
SCHEMBL6580682 0.89 CYP1A2 (0.71) CYP1A2THRBCTRB1MEN1KMT2A
SCHEMBL15424213 0.85 CYP1A2 (0.71) CYP1A2THRBCTRB1MEN1KMT2A
SCHEMBL626036 0.85 CYP1A2 (0.66) CYP1A2THRBCTRB1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252278-B1 Disinfecting agents and their use in disinfecting the skin and mucous membranes HENKEL KGAA (DE) 1998-08-19 EP claimed
US-4560746-A MONOAZO DYES, 2-(2-QUINOLYL)-1,3-INDANEDIONESULFONIC ACID THE HILTON-DAVIS CHEMICAL CO. (US) 1985-12-24 US claimed
US-4084983-A ALUMINUM FLAKES ON A COATING OF ALUMINUM HYDROXIDE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-04-18 US claimed
EP-3906009-B1 MOUSSE-LIKE COSMETIC PREPARATION BEIERSDORF AG (DE) 2024-12-18 EP disclosed
WO-2023111474-A1 DETECTION SYSTEM FOR THE DETECTION OF (A) CHEMICAL COMPOUND(S) BASED ON DISTINCT PARTICLES IMPREGNATED WITH DISTINCT DETECTION INDICATORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-06-22 WO disclosed
WO-2023111475-A1 DETECTION SYSTEM SUITABLE FOR USE IN THE DETECTION OF CHEMICAL COMPOUNDS COMPRISING A DETECTION STRIP COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-06-22 WO disclosed
US-11110121-B2 Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances CLARIANT INTERNATIONAL LTD. (CH) 2021-09-07 US disclosed
US-10406135-B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group CLARIANT INTERNATIONAL LTD. (CH) 2019-09-10 US disclosed
US-9834635-B2 Polymers based on arcrylic, methacrylic or ethacrylic amidoalkyl sulfonic acid or salts and carboxyalky acrylate, methacrylate or ethacrylate or oligomers of said carboxy compounds CLARIANT INTERNATIONAL LTD. (CH) 2017-12-05 US disclosed
US-20170105910-A1 UV FILTER CAPSULE BASF SE (DE) 2017-04-20 US disclosed
US-9592185-B2 Compositions containing hydrogen peroxide or substances releasing hydrogen peroxide CLARIANT INTERNATIONAL LTD. (CH) 2017-03-14 US disclosed
WO-1998023247-A1 AGENT FOR DYEING AND DECOLORIZING FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1998-06-04 WO disclosed
WO-1998022078-A1 AGENTS FOR DYING AND DECOLORIZING FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1998-05-28 WO disclosed
EP-0702232-A1 Process for evaluating the state of human hair GOLDWELL GmbH (DE) 1996-03-20 EP disclosed
US-4900721-A Disinfectants and their use for disinfecting the skin and mucous membrane HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-02-13 US disclosed
US-4560746-A MONOAZO DYES, 2-(2-QUINOLYL)-1,3-INDANEDIONESULFONIC ACID THE HILTON-DAVIS CHEMICAL CO. (US) 1985-12-24 US disclosed
US-4560746-A MONOAZO DYES, 2-(2-QUINOLYL)-1,3-INDANEDIONESULFONIC ACID THE HILTON-DAVIS CHEMICAL CO. (US) 1985-12-24 US disclosed
US-4180467-A SUSTAINED EFFERVESCENCE COLGATE-PALMOLIVE COMPANY (US) 1979-12-25 US disclosed
US-4084983-A ALUMINUM FLAKES ON A COATING OF ALUMINUM HYDROXIDE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-04-18 US disclosed
US-3931144-A NON DIFFUSING PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11110121-B2 Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances GPX4, LPO, CAT CYP1A2 812/4885THRB 2791/4885CTRB1 534/4885
US-20170105910-A1 UV FILTER CAPSULE UROD, MITF, NISCH CYP1A2 201/4885THRB 4752/4885CTRB1 1434/4885
US-10406135-B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group ADH5, ADH1A, ADH1C CYP1A2 42/4885THRB 941/4885CTRB1 1752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.