Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 11/20 | 0.50 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | CD40 | P25942 | 1/20 | 0.43 |
| ▸ | CD40LG | P29965 | 1/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.39 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787589 | 0.88 | ENPP2 (0.49) | ENPP2PHLPP2CA2CA3PRMT3 | |
| SCHEMBL23787693 | 0.86 | PHLPP2 (0.52) | ENPP2PHLPP2CA2CA3PRMT3 | |
| SCHEMBL23787643 | 0.84 | PRMT3 (0.48) | ENPP2PHLPP2CA2CA3PRMT3 | |
| SCHEMBL23787739 | 0.84 | ENPP2 (0.61) | ENPP2PHLPP2CA2CA3PRMT3 | |
| SCHEMBL23787555 | 0.83 | PHLPP2 (0.60) | ENPP2PHLPP2CA2CA3CD40 | |
| SCHEMBL29702399 | 0.82 | ENPP2 (0.58) | ENPP2PHLPP2CA2CA3PRMT3 | |
| SCHEMBL29702431 | 0.81 | ENPP2 (0.59) | ENPP2PHLPP2CA2CA3PRMT3 | |
| SCHEMBL10634937 | 0.81 | ENPP2 (0.58) | ENPP2PHLPP2CA2CA3PRMT3 | |
| SCHEMBL20306679 | 0.80 | ENPP2 (0.54) | ENPP2PHLPP2CA2CA3PRMT3 | |
| SCHEMBL13631321 | 0.80 | ENPP2 (0.54) | ENPP2PHLPP2CA2CA3PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | ACIBADEM MEHMET ALI AYDINLAR UNIVERSITESI (TR) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | POLG, POLB, POLA1 | ENPP2 2691/4885PHLPP2 1195/4885CA2 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.