Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 4/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23790597 | 0.82 | AOC1 (0.38) | AOC1AOC3KDM4C | |
| SCHEMBL20999850 | 0.79 | AOC1 (0.50) | AOC1AOC3KDM4C | |
| SCHEMBL15920595 | 0.71 | AOC1 (0.48) | AOC1AOC3KDM4C | |
| SCHEMBL28151933 | 0.71 | AOC1 (0.44) | AOC1AOC3KDM4C | |
| SCHEMBL20519784 | 0.70 | AOC1 (0.42) | AOC1AOC3KDM4C | |
| SCHEMBL21788802 | 0.67 | AOC1 (0.30) | AOC1AOC3 | |
| SCHEMBL20518940 | 0.67 | AOC1 (0.39) | AOC1AOC3KDM4C | |
| SCHEMBL21652650 | 0.67 | AOC1 (0.39) | AOC1AOC3KDM4C | |
| SCHEMBL23771337 | 0.65 | AOC3 (0.40) | AOC1AOC3 | |
| SCHEMBL30107341 | 0.62 | AOC1 (0.35) | AOC1AOC3KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277024-A1 | NAPHTHYRIDINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277024-A1 | NAPHTHYRIDINE COMPOUNDS AND USES THEREOF | NEK1, NEK11, NEK5 | AOC1 1896/4885AOC3 3469/4885KDM4C 2666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.