SCHEMBL30107341

SCHEMBL30107341

CNc1cncc(OB(O)O)c1C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AOC1 P19801 1/20 0.35
AOC3 Q16853 1/20 0.35
KDM4C Q9H3R0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30107394 0.73 RAF1 (0.33)
SCHEMBL20999850 0.73 AOC1 (0.50) AOC1AOC3KDM4C
SCHEMBL20518940 0.73 AOC1 (0.39) AOC1AOC3KDM4C
SCHEMBL30600890 0.69 PTPN1 (0.35) AOC3
SCHEMBL28365334 0.69 PTPN1 (0.35) AOC3
SCHEMBL27764590 0.66 APP (0.42)
SCHEMBL20519784 0.65 AOC1 (0.42) AOC1AOC3KDM4C
SCHEMBL27685127 0.64 SIRT3 (0.40)
SCHEMBL14940656 0.62 ALDH1A1 (0.35)
SCHEMBL23790633 0.62 AOC1 (0.39) AOC1AOC3KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110678466-B Diazanaphthalenes as HPK1 inhibitors 豪夫迈·罗氏有限公司 2023-01-31 CN disclosed