Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GLS | O94925 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743018 | 0.83 | HPGD (0.61) | HPGDNPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8862940 | 0.82 | GAA (0.60) | HPGDNPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8862746 | 0.82 | GAA (0.60) | HPGDNPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8862856 | 0.82 | GAA (0.60) | HPGDNPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7519591 | 0.82 | GAA (0.60) | HPGDNPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6699936 | 0.80 | GLS (0.71) | RAB9ASMN1; SMN2MAPTNPC1GLS | |
| SCHEMBL3642366 | 0.80 | RAB9A (0.65) | HPGDNPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18461333 | 0.80 | HPGD (0.57) | HPGDNPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL12029182 | 0.80 | HPGD (0.57) | HPGDNPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL15894480 | 0.80 | HPGD (0.57) | HPGDNPSR1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328922-B1 | HYDROXIDE-CATALYZED FORMATION OF SILICON-OXYGEN BONDS BY DEHYDROGENATIVE COUPLING OF HYDROSILANES AND ALCOHOLS | CALIFORNIA INST OF TECHN (US) | 2021-09-08 | — | — | EP | disclosed |