SCHEMBL23793039

SCHEMBL23793039

CC(C)c1sc(Br)nc1-c1ccc(CC(C)c2sc(Br)nc2-c2ccsc2)s1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM5B Q9UGL1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23791829 0.83 KDM5B (0.39) KDM5B
SCHEMBL23791836 0.63 MEN1 (0.42) KDM5B
SCHEMBL6909946 0.63 HTR2A (0.39) KDM5B
SCHEMBL25546337 0.62 FBP1 (0.48) KDM5B
SCHEMBL25558486 0.60 FBP1 (0.46) KDM5B
SCHEMBL10287896 0.59 PRKCI (0.39) —
SCHEMBL26266041 0.59 GRM2 (0.34) —
SCHEMBL23791922 0.59 ALDH1A1 (0.40) —
SCHEMBL23791840 0.59 KDM5B (0.40) KDM5B
SCHEMBL28333549 0.58 ESRRG (0.35) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021178488-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. (US) 2021-09-10 — — WO disclosed
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