SCHEMBL2379351

SCHEMBL2379351

Cc1ccccc1OP(O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
CYP1A2 P05177 3/20 0.41
KDM4E B2RXH2 2/20 0.41
ACHE P22303 1/20 0.41
NOTUM Q6P988 2/20 0.41
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
ALOX15 P16050 1/20 0.38
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
AOC2 O75106 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CYP3A4 P08684 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29769737 1.00 TSHR (0.43) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL594776 0.86 TSHR (0.43) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL27275039 0.84 TSHR (0.42) TSHRMEN1KMT2ASMN1; SMN2NPC1
Tromethamine SCHEMBL21440356 0.84 KDM4E (0.39) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL28087225 0.82 DRD2 (0.37) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL1168100 0.82 MAPT (0.46) MEN1KMT2ARAB9ACYP1A2KDM4E
SCHEMBL27594718 0.82 SMN1; SMN2 (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL2571438 0.82 CA2 (0.38) TSHRKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL25438306 0.80 TSHR (0.39) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL21851530 0.80 TSHR (0.46) TSHRMEN1KMT2ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4190769-A1 APPLICATION OF POLYDENTATE PHOSPHITE LIGAND IN CATALYTIC SYNTHESIS OF ADIPONITRILE Zhejiang University (CN) 2023-06-07 EP claimed
CN-113912516-A Application of multidentate phosphite ligand in catalytic synthesis of adiponitrile 浙江新和成股份有限公司 2022-01-11 CN claimed
CN-107164818-B Nylon fiber and preparation method thereof 江苏海阳化纤有限公司 2020-04-10 CN claimed
EP-3347364-A1 PHOSPHINE OXIDES REDUCTION Rhodia Operations (FR) 2018-07-18 EP claimed
WO-2017041723-A1 PHOSPHINE OXIDES REDUCTION RHODIA OPERATIONS (FR) 2017-03-16 WO claimed
CN-104558582-B Method for preparing polyepichlorohydrin by catalyzing epichlorohydrin polymerization by using three-element iron catalyst 山东菏泽玉皇化工有限公司 2017-01-18 CN claimed
WO-2005010028-A1 ALPHA-AMINO ACID BENZOTHIAZOLYLTHIO ESTER AS INTERMEDIATES FOR MANUFACTURE OF ACE INHIBITORS AND PROCESS FOR PREPARATION THEREOF LUPIN LIMITED (IN) 2005-02-03 WO claimed
US-5602228-A Nickel phosphate catalysts MAXDEM INCORPORATED (US) 1997-02-11 US claimed
WO-1996039455-A1 NICKEL PHOSPHITE CATALYSTS MAXDEM INCORPORATED (US) 1996-12-12 WO claimed
US-4065362-A Purification of organic isocyanates SUMITOMO BAYER URETHANE CO., LTD. (JA) 1977-12-27 US claimed
WO-2024028722-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS INV NYLON CHEMICALS AMERICAS, LLC (US) 2024-02-08 WO disclosed
WO-2024024935-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE HAVING ANTINEOPLASTIC EFFECT 第一三共株式会社 2024-02-01 WO disclosed
EP-4190769-A1 APPLICATION OF POLYDENTATE PHOSPHITE LIGAND IN CATALYTIC SYNTHESIS OF ADIPONITRILE Zhejiang University (CN) 2023-06-07 EP disclosed
CN-112424252-B Thermoplastic polyurethane resin, use thereof, and method for producing same 三井化学株式会社 2023-04-21 CN disclosed
CN-115113484-A Positive photosensitive resin composition, positive photosensitive dry film, method for producing the same, and method for forming pattern 信越化学工业株式会社 2022-09-27 CN disclosed
US-4105540-A PHOSPHORUS CONTAINING COMPOUNDS AS ANTIFOULANTS IN ETHYLENE CRACKING FURNACES NALCO CHEMICAL COMPANY (US) 1978-08-08 US disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed
US-4065362-A Purification of organic isocyanates SUMITOMO BAYER URETHANE CO., LTD. (JA) 1977-12-27 US disclosed
US-4024048-A Organophosphorous antifoulants in hydrodesulfurization NALCO CHEMICAL COMPANY (US) 1977-05-17 US disclosed
US-4024050-A Phosphorous ester antifoulants in crude oil refining NALCO CHEMICAL COMPANY (US) 1977-05-17 US disclosed