Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28900454 | 0.96 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL28224223 | 0.93 | ALDH1A1 (0.35) | — | |
| Fluoride Ion SCHEMBL27920202 | 0.92 | — | — | |
| SCHEMBL19810566 | 0.92 | — | — | |
| Bromide SCHEMBL20529501 | 0.92 | — | — | |
| Fluoride SCHEMBL28193420 | 0.88 | — | — | |
| Water SCHEMBL27847897 | 0.88 | — | — | |
| Bromide SCHEMBL27957832 | 0.88 | ALDH1A1 (0.38) | — | |
| Ethyne SCHEMBL27827153 | 0.85 | ALDH1A1 (0.35) | — | |
| Bromide SCHEMBL28112879 | 0.85 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483274-A | A kind of preparation method of cyclopentolate hydrochloride intermediate | SHANDONG SHENLIAN BIOLOGICAL TECH CO LTD | 2019-11-22 | — | — | CN | claimed |
| CN-110330540-A | Nucleosides salt and preparation method thereof | 木天(济南)生物科技有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-110311126-A | A kind of organic Mg secondary cell of high-energy density | 中国科学院上海硅酸盐研究所 | 2019-10-08 | — | — | CN | claimed |
| CN-109956938-A | Wumei bromine ammonium intermediate crystal form and preparation method thereof and the method that Wumei bromine ammonium is prepared with the intermediate | 天津金耀集团有限公司 | 2019-07-02 | — | — | CN | claimed |
| CN-109956948-A | The synthetic method of natural products (-)-newbouldine | 陕西师范大学 | 2019-07-02 | — | — | CN | claimed |
| CN-109824493-A | The preparation method of one kind 10,10- dimethyl anthrone | 辽宁博美医药科技有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-109449402-A | A kind of nano carbon microsphere supports preparation and its application method of MXene composite material | 北京科技大学 | 2019-03-08 | — | — | CN | claimed |
| CN-107011338-B | A kind of preparation method of Suo Feinaxin impurity | 梯尔希（南京）药物研发有限公司 | 2019-02-19 | — | — | CN | claimed |
| CN-109265385-A | A kind of synthesis technology of chiral catalyst | 上海福乐医药科技有限公司 | 2019-01-25 | — | — | CN | claimed |
| CN-109053495-A | A kind of synthetic method of LCZ696 intermediate | 江苏宇田医药有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-101274938-A | Preparation for (S) or (R)-2-methyl-CBS-chiral oxazaborolidine and toluene solution thereof | SHANGHAI WEIZHI MEDICINE TECHN (CN) | 2008-10-01 | — | — | CN | claimed |
| CN-101151234-A | Process for producing cyclopropylphenol derivative | SANKYO AGRO CO LTD (JP) | 2008-03-26 | — | — | CN | claimed |
| CN-101111500-A | Method of making phenyl-containing chlorosilanes with aliphatic or cycloparaffinic hydrocarbon solvents | DOW CORNING (US) | 2008-01-23 | — | — | CN | claimed |
| CN-101035818-A | Ziegler-natta catalyst, method for the production thereof and use thereof for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-09-12 | — | — | CN | claimed |
| CN-100999452-A | Method of synthesizing seratrodast | UNIV CHONGQING (CN) | 2007-07-18 | — | — | CN | claimed |
| CN-1902208-A | Grignard processes with improved yields of diphenylchlorosilanes as products | DOW CORNING (US) | 2007-01-24 | — | — | CN | claimed |
| CN-1902209-A | Grignard processes with increased content of diphenylchlorosilanes | DOW CORNING (US) | 2007-01-24 | — | — | CN | claimed |
| CN-1759084-A | Process for preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS INC (US) | 2006-04-12 | — | — | CN | claimed |
| CN-1612871-A | Processes and intermediates for preparing benzyl epoxides | ELAN PHARM INC (US) | 2005-05-04 | — | — | CN | claimed |
| CN-1496352-A | Substituted dimethyl- [ 1- (1-phenyl-cyclohexyl) -piperidin-3-ylmethyl ] -amines and their use as analgesics | — | 2004-05-12 | — | — | CN | claimed |