Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21903887 | 1.00 | S100A4 (0.46) | S100A4ALDH1A1MAPTGAANPSR1 | |
| SCHEMBL1081094 | 0.73 | PBRM1 (0.49) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL11358351 | 0.73 | PBRM1 (0.49) | ALDH1A1MAPTGAANPSR1KMT2A | |
| SCHEMBL23985252 | 0.73 | PARP1 (0.39) | ALDH1A1MAPTNPSR1PTPRCKMT2A | |
| SCHEMBL1398203 | 0.72 | S100A4 (0.47) | S100A4ALDH1A1MAPTGPR35CA1 | |
| SCHEMBL10049028 | 0.70 | PRKD3 (0.34) | KMT2A | |
| SCHEMBL7908209 | 0.70 | S100A4 (0.45) | S100A4ALDH1A1MAPTGAANPSR1 | |
| SCHEMBL7896197 | 0.70 | S100A4 (0.45) | S100A4ALDH1A1MAPTGAANPSR1 | |
| SCHEMBL7896203 | 0.70 | S100A4 (0.45) | S100A4ALDH1A1MAPTGAANPSR1 | |
| SCHEMBL7896207 | 0.70 | S100A4 (0.45) | S100A4ALDH1A1MAPTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877364-A1 | ROCK KINASE INHIBITORS | Cervello Therapeutics, LLC (US) | 2021-09-15 | — | — | EP | disclosed |