Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081094 | 0.75 | PBRM1 (0.49) | PRKD3PRKCGPRKCBCDK4PRKCA | |
| SCHEMBL23985252 | 0.75 | PARP1 (0.39) | PRKD3PRKCGPRKCBCDK4PRKCA | |
| SCHEMBL11358351 | 0.75 | PBRM1 (0.49) | PRKD3PRKCGPRKCBCDK4PRKCA | |
| SCHEMBL21903887 | 0.70 | S100A4 (0.46) | KMT2A | |
| SCHEMBL23797113 | 0.70 | S100A4 (0.46) | KMT2A | |
| SCHEMBL21788595 | 0.67 | HTR2C (0.43) | PARP1 | |
| SCHEMBL16213357 | 0.67 | PARP1 (0.50) | PARP1KMT2ATNKS2PBRM1HSD17B10 | |
| SCHEMBL22011499 | 0.66 | GSK3B (0.46) | PARP1KMT2ATNKS2PBRM1HSD17B10 | |
| SCHEMBL22397202 | 0.66 | HSD17B10 (0.51) | PARP1KMT2ATNKS2PBRM1HSD17B10 | |
| SCHEMBL29941489 | 0.66 | HSD17B10 (0.51) | PARP1KMT2ATNKS2PBRM1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |