Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593002 | 1.00 | FAAH (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL10937171 | 1.00 | FAAH (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL27624103 | 1.00 | FAAH (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL23797403 | 1.00 | FAAH (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL4423050 | 1.00 | FAAH (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL10602979 | 0.98 | FAAH (0.50) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL8775347 | 0.91 | CES1 (0.46) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL27656216 | 0.91 | FAAH (0.70) | FAAHSOAT1MEN1KMT2ATP53 | |
| Stearic Acid SCHEMBL28075730 | 0.91 | GPR84 (0.61) | MEN1KMT2ACYP1A2CYP2C19GPR84 | |
| SCHEMBL28013125 | 0.86 | FAAH (0.47) | FAAHSOAT1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876928-A2 | INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION | Merck Sharp & Dohme Corp. (US) | 2021-09-15 | — | — | EP | disclosed |