Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948627 | 0.79 | OPRM1 (0.41) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL12673901 | 0.72 | KDM4E (0.39) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL23442163 | 0.70 | KDM4E (0.46) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL10643969 | 0.69 | KDM4E (0.41) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL14400310 | 0.69 | KDM4E (0.37) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL14137688 | 0.67 | OPRM1 (0.42) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| Oxalic Acid SCHEMBL10644219 | 0.67 | KDM4E (0.41) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL12125715 | 0.66 | SMN1; SMN2 (0.47) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL23108902 | 0.66 | KDM4E (0.35) | OPRM1OPRD1OPRK1SMN1; SMN2KDM4E | |
| SCHEMBL12618705 | 0.66 | KDM4E (0.42) | OPRM1OPRD1OPRK1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178920-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 THERAPEUTICS, INC. (US) | 2021-09-10 | — | — | WO | disclosed |