Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23798141 | 0.79 | OPRM1 (0.35) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL1095665 | 0.79 | KMT2A (0.42) | OPRM1OPRD1OPRK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28484334 | 0.77 | OPRM1 (0.41) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL12673901 | 0.76 | KDM4E (0.39) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL14137688 | 0.75 | OPRM1 (0.42) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL3019549 | 0.75 | — | — | |
| SCHEMBL10232812 | 0.74 | CYP2D6 (0.38) | OPRM1OPRD1OPRK1KDM4E | |
| Oxalic Acid SCHEMBL10644219 | 0.74 | KDM4E (0.41) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL23442163 | 0.74 | KDM4E (0.46) | OPRM1OPRD1OPRK1SMN1; SMN2HSD11B1 | |
| SCHEMBL14033025 | 0.73 | CYP2C19 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |