Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297128 | 0.88 | ACE2 (0.36) | P2RX7ACE2 | |
| SCHEMBL22095896 | 0.81 | ACE2 (0.44) | P2RX7ACE2 | |
| SCHEMBL18999654 | 0.78 | CCR8 (0.33) | P2RX7ACE2 | |
| SCHEMBL27271494 | 0.77 | TSHR (0.34) | P2RX7ACE2 | |
| SCHEMBL25846725 | 0.76 | ACE2 (0.33) | P2RX7ACE2 | |
| SCHEMBL15826672 | 0.76 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL18975746 | 0.76 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL12278113 | 0.73 | GPR55 (0.39) | P2RX7 | |
| SCHEMBL12278257 | 0.72 | AHR (0.38) | P2RX7 | |
| SCHEMBL12278916 | 0.72 | TNF (0.36) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178920-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 THERAPEUTICS, INC. (US) | 2021-09-10 | — | — | WO | disclosed |