Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.58 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | SELP | P16109 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24760591 | 0.94 | CASP2 (0.53) | FAAHDNM1CASP2NAAACNR1 | |
| SCHEMBL16085238 | 0.89 | FAAH (0.66) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL19477959 | 0.89 | CASP2 (0.69) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL26886295 | 0.89 | FAAH (0.66) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL26301627 | 0.88 | FAAH (0.59) | FAAHDNM1CASP2NAAACNR1 | |
| SCHEMBL22341393 | 0.86 | CASP2 (0.66) | FAAHDNM1CASP2NAAACNR1 | |
| SCHEMBL1630120 | 0.85 | FAAH (0.73) | FAAHDNM1CASP2NAAACNR1 | |
| SCHEMBL24943604 | 0.84 | FAAH (0.50) | FAAHDNM1CASP2NAAACNR1 | |
| SCHEMBL25008200 | 0.83 | FAAH (0.77) | FAAHDNM1CASP2NAAACNR1 | |
| SCHEMBL227920 | 0.83 | FAAH (0.77) | FAAHDNM1CASP2NAAACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178818-A2 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2021-09-10 | — | — | WO | disclosed |