Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12419169 | 0.81 | LMNA (0.52) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL16906272 | 0.79 | LMNA (0.50) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL28969201 | 0.78 | LMNA (0.48) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL28969199 | 0.78 | LMNA (0.49) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL17882061 | 0.78 | LMNA (0.48) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL23798618 | 0.77 | LMNA (0.57) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL11861904 | 0.77 | ELANE (0.51) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL15965768 | 0.77 | LMNA (0.47) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL13225899 | 0.76 | LMNA (0.59) | LMNAELANEGAAALDH1A1KMT2A | |
| SCHEMBL891415 | 0.76 | ELANE (0.68) | LMNAELANEGAAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178818-A2 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2021-09-10 | — | — | WO | disclosed |