Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.56 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 4/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | TK2 | O00142 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531136 | 1.00 | RNASE1 (0.56) | RNASE1TYMSTK1TYMPTK2 | |
| SCHEMBL5531135 | 1.00 | RNASE1 (0.56) | RNASE1TYMSTK1TYMPTK2 | |
| SCHEMBL23045153 | 0.94 | RNASE1 (0.57) | RNASE1TYMSTK1TYMPTK2 | |
| SCHEMBL8749986 | 0.92 | RNASE1 (0.68) | RNASE1TYMSTK1TYMPTK2 | |
| SCHEMBL17230824 | 0.92 | RNASE1 (0.53) | RNASE1TYMSTK1TYMPTK2 | |
| SCHEMBL1311805 | 0.91 | RNASE1 (0.46) | RNASE1TYMSTK1TYMP | |
| SCHEMBL6830771 | 0.91 | RNASE1 (0.51) | RNASE1TYMSTK1TYMP | |
| SCHEMBL5402296 | 0.91 | RNASE1 (0.53) | RNASE1TYMSTK1 | |
| SCHEMBL30287884 | 0.91 | RNASE1 (0.53) | RNASE1TYMSTK1 | |
| SCHEMBL23996825 | 0.91 | RNASE1 (0.53) | RNASE1TYMSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026348-B2 | Nucleoside derivative, modified oligonucleotide, method for their synthesis and applications thereof | LESNIKOWSKI ZBIGNIEW J | 2011-09-27 | — | — | US | disclosed |