SCHEMBL5402296

SCHEMBL5402296

COc1ccc(C(OC[C@H]2O[C@@H](n3cc(C)c(=O)[nH]c3=O)C[C@@H]2OC(=O)CCC(=O)O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.53
ABCG2 Q9UNQ0 3/20 0.41
ABCB1 P08183 1/20 0.41
TYMS P04818 1/20 0.41
TK1 P04183 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30287884 1.00 RNASE1 (0.53) RNASE1ABCG2ABCB1TYMSTK1
SCHEMBL23996825 1.00 RNASE1 (0.53) RNASE1ABCG2ABCB1TYMSTK1
SCHEMBL17230824 0.95 RNASE1 (0.53) RNASE1ABCG2ABCB1TYMSTK1
SCHEMBL23045153 0.92 RNASE1 (0.57) RNASE1TYMSTK1
SCHEMBL6303992 0.91 RNASE1 (0.52) RNASE1TYMSTK1
SCHEMBL2379935 0.91 RNASE1 (0.56) RNASE1TYMSTK1
SCHEMBL5531136 0.91 RNASE1 (0.56) RNASE1TYMSTK1
SCHEMBL5531135 0.91 RNASE1 (0.56) RNASE1TYMSTK1
SCHEMBL8749986 0.89 RNASE1 (0.68) RNASE1TYMSTK1
SCHEMBL6830771 0.88 RNASE1 (0.51) RNASE1TYMSTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7201844-B1 Composite matrices with interstital polymer networks HAMMEN CORPORATION (US) 2007-04-10 US disclosed
EP-1448789-A4 DEVICE AND METHODS FOR DIRECTED SYNTHESIS OF CHEMICAL LIBRARIES NANOMICS BIOSYSTEMS PTY LTD (AU) 2007-01-03 EP disclosed
US-6946070-B2 Composite matrices with interstitial polymer networks HAMMEN CORPORATION 2005-09-20 US disclosed
EP-1448789-A2 DEVICE AND METHODS FOR DIRECTED SYNTHESIS OF CHEMICAL LIBRARIES Nanomics Biosystems Pty, Ltd. (AU) 2004-08-25 EP disclosed
US-20030182068-A1 Device and methods for directed synthesis of chemical libraries NANOMICS BIOSYSTEMS PTY LTD (AU) 2003-09-25 US disclosed
WO-2003038558-A2 DEVICE AND METHODS FOR DIRECTED SYNTHESIS OF CHEMICAL LIBRARIES NANOMICS BIOSYSTEMS PTY, LTD. (AU) 2003-05-08 WO disclosed
EP-1274503-A2 COMPOSITE MATRICES WITH INTERSTITIAL POLYMER NETWORKS Hammen Corporation (US) 2003-01-15 EP disclosed
US-20020043499-A1 Composite matrices with interstitial polymer networks HAMMEN CORPORATION 2002-04-18 US disclosed
WO-2001068240-A2 COMPOSITE MATRICES WITH INTERSTITIAL POLYMER NETWORKS HAMMEN CORPORATION (US) 2001-09-20 WO disclosed