SCHEMBL23801848

SCHEMBL23801848

CC(C)(C)OC(=O)n1c2c(c3ccccc31)C(=O)CCC2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.49
CREBBP Q92793 1/20 0.49
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
HDAC1 Q13547 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
GLP1R P43220 2/20 0.40
TSHR P16473 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ACHE P22303 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CCNB2 O95067 1/20 0.38
CDK1 P06493 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30511849 1.00 TP53 (0.49) TP53CREBBPCHRM2CHRM4CHRM1
SCHEMBL28883032 0.84 TSHR (0.55) TP53CREBBPCHRM2CHRM4CHRM1
SCHEMBL23801864 0.79 TP53 (0.54) TP53CREBBPHDAC1HDAC6PTGS1
SCHEMBL8791684 0.78 TP53 (0.60) TP53CREBBPCHRM2CHRM4CHRM1
SCHEMBL2241939 0.78 PTGS1 (0.49) CHRM2CHRM4CHRM1CHRM3HDAC1
SCHEMBL13696680 0.77 CHRM2 (0.59) CHRM2CHRM4CHRM1CHRM3L3MBTL1
SCHEMBL30022454 0.77 CHRM2 (0.59) CHRM2CHRM4CHRM1CHRM3L3MBTL1
SCHEMBL30452765 0.77 CHRM2 (0.46) CREBBPCHRM2CHRM4CHRM1CHRM3
SCHEMBL22708510 0.75 TP53 (0.46) TP53CREBBPHDAC1HDAC6PTGS1
SCHEMBL17897786 0.74 CHRM2 (0.50) CHRM2CHRM4CHRM1CHRM3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334454-B Environment-friendly olefin hydration reaction 佐治亚州立大学研究基金会公司 2024-04-30 CN disclosed
US-11708320-B2 Environmentally-friendly hydroazidation of olefins GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-07-25 US disclosed
US-11708320-B2 Environmentally-friendly hydroazidation of olefins GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-07-25 US disclosed
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-09-16 US disclosed
CN-112334454-A Environmentally friendly olefin hydration reactions 佐治亚州立大学研究基金会公司 2021-02-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708320-B2 Environmentally-friendly hydroazidation of olefins HAO2, AHR, HMOX1 TP53 1404/4885CREBBP 2266/4885CHRM2 4323/4885
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS HAO2, AHR, HMOX1 TP53 1404/4885CREBBP 2266/4885CHRM2 4323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.