Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676890 | 0.95 | CYP19A1 (0.38) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL15709374 | 0.94 | CYP19A1 (0.38) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL21854598 | 0.90 | NOTUM (0.41) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL305812 | 0.87 | CYP19A1 (0.34) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL3934311 | 0.86 | CYP19A1 (0.33) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL306997 | 0.82 | CYP19A1 (0.41) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL15455875 | 0.81 | ALDH1A1 (0.36) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL12398885 | 0.80 | NOTUM (0.41) | — | |
| SCHEMBL17157379 | 0.79 | CYP19A1 (0.37) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL1365427 | 0.79 | CA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2021-09-16 | — | — | US | disclosed |
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | ITGB1, ITGAV, ITGA1 | CYP19A1 3584/4885UGT1A4 1257/4885PDE4D 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.