Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 7/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055197 | 0.71 | KMT2A (0.51) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14515856 | 0.69 | HCAR2 (0.64) | RAB9APLK1PLK3HCAR2 | |
| SCHEMBL18520605 | 0.68 | HCAR2 (0.77) | RAB9AHCAR2 | |
| SCHEMBL14290089 | 0.68 | RAB9A (0.52) | MEN1KMT2ARAB9AGAAHCAR2 | |
| SCHEMBL6891543 | 0.68 | KMT2A (0.55) | KDM4EALDH1A1MEN1KMT2APLK1 | |
| SCHEMBL20355814 | 0.67 | GAA (0.50) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL14290037 | 0.67 | HCAR2 (0.51) | RAB9AGAAHCAR2 | |
| SCHEMBL14289936 | 0.67 | HCAR2 (0.58) | RAB9AGAAHCAR2 | |
| SCHEMBL9866534 | 0.67 | GAA (0.46) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20339451 | 0.66 | GAA (0.58) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021176074-A1 | COMPOSITION COMPRISING AN AVENANTHRAMIDE WITH IMPROVED SKIN PENETRATION | SYMRISE AG (DE) | 2021-09-10 | — | — | WO | disclosed |