Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335841 | 0.83 | HDAC3 (0.56) | GAAHDAC3HDAC1KMT2AHDAC4 | |
| SCHEMBL9866523 | 0.80 | HTT (0.49) | HDAC3HDAC1ALDH1A1SMN1; SMN2HDAC8 | |
| SCHEMBL9335939 | 0.76 | HDAC3 (0.39) | GAAHDAC3HDAC1GCGRSMN1; SMN2 | |
| SCHEMBL29902900 | 0.73 | GAA (0.58) | GAAHDAC3HDAC1KMT2AKDM4E | |
| SCHEMBL20339451 | 0.73 | GAA (0.58) | GAAHDAC3HDAC1KMT2AKDM4E | |
| SCHEMBL12855992 | 0.69 | CSNK2A1 (0.54) | GAAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL279847 | 0.68 | NPC1 (0.51) | KMT2AGCGRHPGDHSD17B10MEN1 | |
| SCHEMBL22822046 | 0.67 | LTA4H (0.47) | GAAHDAC3HDAC1KMT2AHDAC4 | |
| Dodecanoate SCHEMBL7192361 | 0.67 | GAA (0.60) | GAAHDAC3HDAC1KMT2AKDM4E | |
| SCHEMBL23802409 | 0.67 | KDM4E (0.44) | GAAHDAC3HDAC1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |