Squalene

Squalene

SCHEMBL890053

CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C.CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 1.00
SQLE Q14534 8/20 0.81
MAPT P10636 2/20 0.76
MEN1 O00255 2/20 0.76
CYP3A4 P08684 2/20 0.76
ALOX15 P16050 2/20 0.76
ALDH1A1 P00352 1/20 0.76
UGT1A1 P22309 1/20 0.76
KDM4E B2RXH2 1/20 0.67
FNTA P49354 1/20 0.59
FNTB P49356 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Squalene SCHEMBL31125292 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL4444267 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL2799805 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL8819997 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
SCHEMBL8013144 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
SCHEMBL23802597 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
SCHEMBL39067 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
SCHEMBL21639794 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL21823197 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL29525662 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117099778-B Application of dimethyl sulfide as six-spot Ping Yanya fly attractant 中国农业科学院草原研究所 2024-01-05 CN disclosed
CN-117099778-A Application of dimethyl sulfide as six-spot Ping Yanya fly attractant 中国农业科学院草原研究所 2023-11-24 CN disclosed
CN-105567578-B A kind of ganoderic acid high-yielding engineering bacterial strain kmust-SE 昆明理工大学 2019-02-19 CN disclosed
CN-108618057-A A kind of squalene nutritional jelly and preparation method thereof 安阳工学院 2018-10-09 CN disclosed
CN-104784687-A Application of flagellar hook protein FlgE of reorganized pseudomonas aeruginosa FIRST AFFILIATED HOSPITAL SOOCHOW UNIV 2015-07-22 CN disclosed
CN-103272065-B Application and application of volatile oil extracted from agilawood seeds by supercritical carbon dioxide ZHONGSHAN HOSPITAL TCM 2015-04-15 CN disclosed
US-20110289606-A1 EQUINE DISEASE MODEL FOR HERPESVIRUS NEUROLOGIC DISEASE AND USES THEREOF UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2011-11-24 US disclosed
EP-2306812-A2 EQUINE DISEASE MODEL FOR HERPESVIRUS NEUROLOGIC DISEASE AND USES THEREOF University of Kentucky Research Foundation (US) 2011-04-13 EP disclosed
US-20100204254-A1 Use of statins in the prevention and treatment of radiation injury and other disorders associated with reduced endothelial thrombomodulin THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES (US) 2010-08-12 US disclosed
US-20100183662-A1 VACCINE COMPRISING STREPTOCOCCUS PNEUMONIAE CAPSULAR POLYSACCHARIDE CONJUGATES GLAXOSMTHKLINE BIOLOGICALS, S.A. (BE) 2010-07-22 US disclosed
US-20090191226-A2 ADJUVANT FORMULATION COMPRISING A SUBMICRON OIL DROPLET EMULSION NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2009-07-30 US disclosed
CN-200994863-Y Health-care paper pants containing tea-seed essence WEI CAO (CN) 2007-12-26 CN disclosed
WO-2007017916-A2 QUALITATIVE ASSAY OF EXTRA-VIRGIN OLIVE OILS IPPOLITO FERDINANDO (IT) 2007-02-15 WO disclosed
WO-2004024073-A2 USE OF STATINS IN THE PREVENTION AND TREATMENT OF RADIATION INJURY AND OTHER DISORDERS ASSOCIATED WITH REDUCED ENDOTHELIAL THROMBOMODULIN THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2004-03-25 WO disclosed
EP-1183275-A2 COMBINED APPROACH TO TREATMENT OF CANCER WITH HCG VACCINES Avi Biopharma, Inc. (US) 2002-03-06 EP disclosed
WO-2000069915-A2 COMBINED APPROACH TO TREATMENT OF CANCER WITH hCG VACCINES AVI BIOPHARMA, INC. (US) 2000-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090191226-A2 ADJUVANT FORMULATION COMPRISING A SUBMICRON OIL DROPLET EMULSION MYD88, CD14, IAPP KMT2A 3695/4885SQLE 138/4885MAPT 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.